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10.1001/jama.2008.600

In conclusion, the present review summarized the role of ferroptosis in the pathology of AD and how mechanisms such as iron metabolism disorders, lipid peroxidation and GSH depletion lead to neuronal damage, as well as the role of ferroptosis inhibitors such as vitamin E, Se and Fer-1 as potential therapeutic strategies
Since iron is a well known catalyst for generation of ROS, it is not surprising that oxidative stress is a common finding in iron overload conditions [23]

ADP-ribosyl cyclase allows for synthesis from nicotinamide in the salvage pathway, and NADP + phosphatase can convert NADPH back to NADH to maintain a balance

Green tea is a beverage rich in polyphenols, which are powerful antioxidants that reduce melanin production by inhibiting tyrosinase activity

Supports immune defense mechanisms
