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Combination users were matched, in a 1:1 ratio, to patients prescribed the same background drug, duration of background drug, and time conditional propensity score
Any-grade adverse events were more common among the semaglutide group with the most common being mild-to-moderate severity gastrointestinal symptoms

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Legare de receptorii GLP-1: Tirzepatide activeaz receptorii GLP-1 din pancreas, sistemul nervos central i tractul gastrointestinal, ceea ce duce la stimularea dependent de glucoz a secreiei de insulin i la suprimarea eliberrii glucagonului
